This is a large study with long-term follow-up of subjects with PMD treated with crosslinking. ![]() None of the subjects presented any complication related or not to the procedure. Statistical significant differences were found in visual acuity from 0.44 ± 0.40 to 0.25 ± 0.26 logMAR (p=0.007). Paired t test and STATA 8.0 were used for statistical analysis. Visual acuity (VA), mean keratometries (KM), corneal astigmatism, intraocular pressure (IOP), spherical equivalent (SE) and pachymetry were compared preoperatively and postoperatively with a mean follow-up of 13.89 months (range 3 to 24 months). Nineteen eyes of 13 patients (8 women) were included, mean age was 33.78 years (range 14 to 46). We performed a retrospective, observational clinical study to learn about the clinical and topographic changes after CXL in PMD, and to determine safety and effectiveness of this treatment option to prevent disease progression.Ĭlinical charts from year 2008 to 2016 of subjects diagnosed with PMD who were treated with CXL were reviewed. ![]() This entity has been evaluated much less than keratoconus especially with regard to CXL treatment. ![]() Pellucid marginal degeneration (PMD) is a rare ectatic disorder with steepening and thinning in the peripheral cornea which may also, as keratoconus, benefit from corneal collagen crosslinking (CXL).
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